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Thursday 7th December 2017
Ensuring amorphous product quality: what are the challenges?
Royal Society of Chemistry, London
Purpose of meeting:
Amorphous drug formulation offers great promise in improving drug solubility - a major challenge in drug development. However, poor physical stability and hard to predict crystallisation remains key barriers for the wider use of amorphous solid solution in the pharmaceutical industry. This symposium will critically examine the challenges and opportunities lie in the analysis of amorphous formulation systems. Leading industrialists and academics will be sharing their experiences in the development, manufacturing and quality assurance of amorphous products. New analytical technologies for the prediction of amorphous stability and novel PAT will be discussed.
Challenge:
Is amorphous system still an attractive formulation strategy?
How to ensure reliable manufacturing of amorphous solution formulation?
How to maintain drug in amorphous form for the duration of the shelf life?
What are the latest technologies to ensure the quality of amorphous product?
How to lower the cost for the development and manufacturing of these formulations?
Opportunities:
Better understanding of amorphous system and advancement of analytical techniques will help in the development and optimisation of novel formula.
Proposed outcomes:
You will gain latest knowledges on the analysis and manufacturing of amorphous/solid solution products. You may form new collaborations with experts across academic and industry.

Posters are welcome; Please submit an abstract to ka_lung.chan@kcl.ac.uk

Speakers:
Prof Gavin Andrews - Queen's University Belfast
Prof Duncan Craig - University College London
Dr Korbinian Löbmann - University of Copenhagen
Dr Claire Pizzey - Diamond Light Source
Hans Platteeuw - Avivia
Dr Paul Royall - King's College London
Dr Abhishek Singh - Johnson & Johnson
Dr Krzysztof Sollohub - Catalent




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